Table 2.
Cox regression analysis for incident cerebrovascular disease according to baseline variables among 88 hemodialysis patients
| Univariable | Multivariable | |||
|---|---|---|---|---|
| HR(95% CI) | P | HR(95% CI) | P | |
| Age, years | 1.086 (1.037–1.138) | 0.001** | 1.104 (1.038–1.174) | 0.002** |
| Male, n (%) | 1.667 (0.632–4.392) | 0.302 | ||
| Diabetes history, n (%) | 2.489 (0.927–6.680) | 0.070 | ||
| Hypertension, n (%) | 1.500 (0.437–5.148) | 0.519 | ||
| Tobacco smoking, n (%) | 1.083 (0.297–3.951) | 0.904 | ||
| HD vintage (months) | 1.027 (1.002–1.053) | 0.033* | 1.027 (0.996–1.058) | 0.086 |
| Klotho (pg/ml) | 0.977 (0.965–0.990) | 0.001** | 0.975 (0.960–0.990) | 0.001** |
| Hb (g/L) | 1.006 (0.977–1.063) | 0.679 | ||
| Ca (mmol/L) | 1.298 (0.217–7.772) | 0.775 | ||
| P (mmol/L) | 0.707 (0.291–1.718) | 0.444 | ||
| PTH (pg/ml) | 0.999 (0.997–1.000) | 0.095 | ||
| SF (ng/ml) | 0.996 (0.909–1.091) | 0.931 | ||
| Serum iron (umol/L) | 1.000 (0.998–1.001) | 0.395 | ||
| TIBC (umol/L) | 0.997 (0.949–1.048) | 0.913 | ||
| Tch (mmol/L) | 1.249 (0.794–1.964) | 0.336 | ||
| TG (mmol/L) | 1.448 (0.900–2.330) | 0.127 | ||
| LDL-C (mmol/L) | 1.421 (0.756–2.669) | 0.275 | ||
| HDL-C (mmol/L) | 0.382 (0.073–2.004) | 0.255 | ||
| ALB (g/L) | 0.899 (0.778–1.038) | 0.145 | ||
Hb hemoglobin, Ca calcium, P phosphate, PTH parathyroid hormone, SF serum ferritin, TIBC Total iron binding capacity, Tch total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, ALB albumin, HR hazard ratio, 95% CI 95% confidence interval
*p < 0.05; **p < 0.01