Table 2.
Disease Characteristics, Past Illnesses, and Surgical History
| Category | CAPTURE (N = 150) |
|---|---|
| Mean (±SD) time from diagnosis to discharge, d | 10.1 (±42.0) |
| Disease characteristics, n (%) | |
| Associated with hardware | 32 (21.3) |
| Associated complicationsa | |
| Any | 132 (88.0) |
| ABSSSI | 99 (66.0) |
| Secondary bacteremia | 25 (16.7) |
| Other | 18 (12.0) |
| Primary site of infectiona | |
| Foot | 84 (56.0) |
| Spine | 24 (16.0) |
| Leg or thigh | 18 (12.0) |
| Hip | 13 (8.7) |
| Other | 17 (11.3) |
| Laboratory results,b | |
| Mean (±SD) total white blood cell count, cells/mm3 | 9703.4 (±4228.5) |
| Mean (±SD) serum creatinine, mg/dL | 1.6 (±2.0) |
| Mean (±SD) hemoglobin A1cc | 8.1 (±2.1) |
| Past illnesses,a n (%) | |
| DM | 87 (58.0) |
| PAD | 23 (15.3) |
| DM or PAD | 89 (59.3) |
| DM and PAD | 21 (14.0) |
| Current or recent IV drug use | 2 (1.3) |
| Surgical history during CPT-F therapy,a n (%) | |
| Amputation | 10 (6.7) |
| Incision and drainage | 4 (2.7) |
| Debridement | 3 (2.0) |
| Other | 5 (3.3) |
ABSSSI acute bacterial skin and skin structure infection, CPT-F ceftaroline fosamil, DM diabetes mellitus, IV intravenous, PAD peripheral arterial disease, SD standard deviation
aCategories not mutually exclusive
bBefore treatment with CPT-F
cMeasurements taken 2 months before treatment through the end of treatment