Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 22;9:2594. doi: 10.1038/s41598-019-39141-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Differentially Expressed Genes Following Mild and Moderate IOP Elevation. (a,b) Volcano plots of significantly (FDR < 0.1) differently expressed genes (DEGs) for both Mild (a) and Moderate (b) IOP levels (above dotted line). Upregulated DEGs (Log₂ fold change of ≥0.5849 or ≥1.5-fold change) and downregulated DEGs (Log₂ fold change of ≤−0.5849 or ≤0.666-fold change), are indicated in green and red, respectively. Genes with Log₂ Fold change of <|0.5849| are not significant (black). (c) Venn Diagram depicting the overlap of significant (FDR < 0.1) candidate DEGs in the Mild and Moderate IOP groups (does not include fold-change criteria). (d,e) Venn Diagrams of overlapping significantly (FDR < 0.1 and Log₂ fold change of ≥|0.5849|) identified for up- (d) and down- (e) regulated DEGs.