Table 1.
Top Up- and Down-regulated Genes Following Mild Elevation of IOP.
| Gene Symbol | Gene Name | Gene Accession | Control FPKM Value | Mild IOP FPKM Value | Log2 Fold-Change | Adjusted P-value |
|---|---|---|---|---|---|---|
| Upregulated | ||||||
| Hist3h2bb-ps | histone cluster 3 H2B family member b | NM_206882 | 0.00 | 2.84 | ∞ | 2.15E-03 |
| Tsacc | TSSK6 activating cochaperone | NM_029801 | 0.00 | 2.63 | ∞ | 2.20E-03 |
| Gm20257 | caspase 8 pseudogene | NR_045007 | 0.00 | 1.89 | ∞ | 5.00E-05 |
| Mterf1b | mitochondrial transcription termination factor 1 | NM_001042670 | 0.00 | 1.81 | ∞ | 5.00E-05 |
| Car4 | carbonic anhydrase 4 | NM_007607 | 0.00 | 1.77 | ∞ | 5.00E-05 |
| Downregulated | ||||||
| Crygs | crystallin gamma S | NM_009967 | 85.86 | 0.00 | −∞ | 5.00E-05 |
| Cryba1 | crystallin beta A1 | NM_009965 | 73.73 | 0.00 | −∞ | 5.00E-05 |
| Crygb | crystallin gamma B | NM_144761 | 18.35 | 0.00 | −∞ | 5.00E-05 |
| Crygc | crystallin gamma C | NM_007775 | 14.24 | 0.00 | −∞ | 5.00E-05 |
| Gm4013 | Predicted gene 4013 | NR_033452 | 4.83 | 0.00 | −∞ | 7.00E-04 |