Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 21;9:2482. doi: 10.1038/s41598-019-38906-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Predictive modeling of H1N1-specific B cells. For classification of HIV vs HC, (A) Receiver operating characteristic (ROC) curve for two-class neural network showing prediction accuracy of 0.864. Single cell gene expression data for 33 genes was split 2:1 for train: test. (B) Z score heat map (scaled by gene) showing ‘test’ set of single cells with prediction and actual grouping based on 4-gene signature. For classification of Vaccine Responder and Non-Responder for HIV and HC: (C) Graphical representation of LASSO-PLSDA model using 5-gene signature to segregate 4 groups: HC R, HC NR, HIV R, HIV NR. (D) Classification matrix for the 4 groups showing performance of the model by prediction accuracy for each group. (E) Z score heat map (scaled by gene) showing ‘test’ set of single cells with prediction and actual grouping based on 4-gene signature.