. Author manuscript; available in PMC: 2019 Feb 22.

Published in final edited form as: Adv Exp Med Biol. 2018;1032:115–126. doi: 10.1007/978-3-319-98788-0_9

Table 3.

Changes in hepatic sphingosine signaling mediators in response to EtOH and EtOH/SOY diets in saline-treated male mice [29].

			mRNA expression (fold change)
	SPKH1 membrane expression
		SPKH1	ASAH1	S1PR1	S1PR2	S1PR3
Chow	--	1.00±0.05^a	1.00±0.04^a	1.00±0.16^a	1.00±0.10^a	1.00±0.14^a
EtOH	1.60±0.15	23.45±5.67^b	1.70±0.29^a’^b	0.96±0.22^a	3.59±0.93^b	2.64±0.54^b
EtOH/SOY	0.70±0.08^*	9.12±2.20^a	0.79±0.17^a	0.54±0.09^a	1.31±0.28^a	1.36±0.30^a

Data is expressed as mean ± St.Err; Groups: chow (n=5), EtOH (n=10), EtOH/SOY (n=10). Gene expression and protein determination were determined as previously described (Mercer et al., 2016), Significance, a<b<c, (p<0.05), Student’s T-Test

p<0.05.