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Stable states for ERBB receptor-regulated G1/S transition obtained by PINT software (Paulevé, 2017).
| AKT1 | CDK2 | CDK4 | CDK6 | CycD1 |
|---|---|---|---|---|
| 0 | 0 | 0 | 0 | 0 |
| 1 | 1 | 1 | 1 | 1 |
| 1 | 1 | 1 | 1 | 1 |
| CycE1 | EGF | ERBB1 | ERBB1_2 | ERBB1_3 |
| 0 | 0 | 0 | 0 | 0 |
| 1 | 0 | 0 | 0 | 0 |
| 1 | 1 | 1 | 1 | 1 |
| ERBB2 | ERBB2_3 | ERBB3 | ERalpha | IGF1R |
| 0 | 0 | 0 | 0 | 0 |
| 0 | 0 | 0 | 1 | 1 |
| 1 | 1 | 1 | 1 | 0 |
| MEK1 | MYC | p21 | p27 | pRB |
| 0 | 0 | 0 | 0 | 0 |
| 1 | 1 | 0 | 0 | 1 |
| 1 | 1 | 0 | 0 | 1 |
