Table 1. Computed rate constants and 95% confidence intervals for the barnase–barstar binding process.
Process | Rate constant | Value |
Unbound state → encounter complex | k 1 (M–1 s–1) | 1.8 ± 0.2 × 109 |
Encounter complex → bound state | k 2 (s–1) | 2.7 ± 0.5 × 1010 |
Unbound state → bound state | k on (M–1 s–1) | 2.3 ± 1.0 × 108 |
Experimental kon (ref. 19) (M–1 s–1) | 2.86 ± 0.67 × 108 |