Table 4.
Distribution of anemia and its parameters among different stages of chronic kidney disease in white South Africans
| Stage I | Stage II | Stage IIIa | Stage IIIb | Stage IV | Stage V | Total (n=258) | P-value | |
|---|---|---|---|---|---|---|---|---|
| Anemia status, n (%) | ||||||||
| Anemic | 1 (50.0) | 0 (0.0) | 1 (11.1) | 6 (37.5) | 6 (33.3) | 4 (100.0) | 18 (34.6%) | 0.036 |
| Non-anemic | 1 (50.0) | 3 (100.0) | 8 (88.9) | 10 (62.5) | 12 (66.7) | 0 (0.0) | 34 (65.4%) | |
| Hb (g/dL), mean ± SD | 12.6±0.99 | 16.4±0.85 | 13.3±2.0 | 13.3±2.0 | 13.0±2.3 | 8.1±0.79 | 13.0±2.5 | 0.0001a |
| MCV (fL), mean ± SD | 90.7±1.6 | 90.9±3.5 | 91.2±5.7 | 91.8±8.6 | 90.5±11.8 | 87.5±4.1 | 90.8±8.7 | 0.979a |
| MCH (pg), mean ± SD | 31.7±1.6 | 29.8±0.38 | 30.1±2.1 | 29.7±3.1 | 29.8±3.0 | 27.4±0.17 | 29.7±2.7 | 0.51a |
| MCHC, mean ± SD | 30.7±0.8 | 32.8±1.0 | 32.5±0.9 | 31.3±2.5 | 32.1±1.2 | 31.4±1.6 | 31.8±1.7 | 0.394a |
| CRP (mg/L), mean ± SD | 10.0±0.0 | 17.3±6.4 | 45.6±10.4 | 17.4±16.4 | 20.4±2.5 | 91.3±9.7 | 28.7±5.5 | 0.179a |
| CRP groups, n (%) | ||||||||
| Inflammation (CRP ≥10) | 0 (0.0) | 2 (66.7) | 4 (44.4) | 6 (37.5) | 7 (38.9) | 3 (75.0) | 22 (42.3) | 0.619b |
| No inflammation (CRP <10) | 2 (100.0) | 1 (33.3) | 5 (55.6) | 10 (62.5) | 11 (61.1) | 1 (25.0) | 30 (57.7) |
Notes:
a
ANOVA;
b
Fisher’s exact test;
c
Pearson’s chi-squared text.
Abbreviations: CRP, C-reactive protein; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume.