Table 3.

Antiviral potencies in cells infected with HIV-1 containing wild-type (WT) or mutant integrase enzymes.^a

No.	CC50 (μM)	EC50 (μM, WT)	Mutantsb
			G140S/Q148H	Y143R	N155H
1	>100	0.004 ± 0.002	475x	41x	38x
2	>100	0.017 ± 0.004	5x	0.4x	1x
3	5.4 ± 1.3	1.7 ± 0.5	5x	1x	3x
5e	392 ± 66	9.2 ± 1.9	2x	2x	3x

^aData was obtained as described in the Experimental Section.

^bFold-loss of potency relative to virus containing WT enzyme.