Table 2. Benjamini-Hochberg-False Discovery Rate (BH-FDR) and Fold-Change (FC) for the top genes significantly dysregulated (with nominal P < 0.01) in the EdgeR non- repeated measures analysis in Peripheral Blood Mononuclear Cells at Post-Deployment from Soldiers Returning from Tour in Afghanistan within one-year. *DISC = discretized model; CONT = continuous model.
| Gene Symbol | Entrez Gene ID | edgeR disc/cont | edgeR FC | edgeR P-value | edgeR BH-FDR all genes | edgeR BH-FDR all neuro | edgeR BH-FDR neurobeh av |
|---|---|---|---|---|---|---|---|
| LRP8 | 7804 | DISC | 1.19 | 6.58E-05 | 48% | 17% | 12% |
| CONT | 1.01 | 1.25E-04 | 74% | 37% | 25% | ||
| GOLM1 | 51280 | DISC | 1.22 | 1.16E-04 | 48% | 17% | 12% |
| CONT | 1.01 | 7.68E-04 | 100% | 92% | 63% | ||
| CYP2C8 | 1558 | DISC | 0.51 | 6.32E-05 | 48% | NA | NA |
| CONT | 0.98 | 8.04E-04 | 100% | NA | NA | ||
| LINC00943 | 100507206 | DISC | 1.84 | 1.18E-04 | 48% | NA | NA |
| CONT | 1.02 | 1.31E-04 | 74% | NA | NA | ||
| LOC1001322 15 | 100132215 | DISC | 1.49 | 1.42E-04 | 48% | NA | NA |
| CONT | 1.01 | 4.26E-04 | 100% | NA | NA |