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. Author manuscript; available in PMC: 2019 Feb 22.
Published in final edited form as: Exp Eye Res. 2017 Mar 20;159:58–68. doi: 10.1016/j.exer.2017.03.009

Figure 1.

Figure 1.

Mice simultaneously deficient in SOD1, DJ-1 and Parkin (triple KO, TKO) have a marked increase in retinal injury after exposure to the fundus camera-delivered light induced retinal degeneration (FCD-LIRD) models, when compared to C57BL/6J mice. Fundus photos were obtained at baseline (A-F) or 5 days after light exposure (G-W). In experiment 1 (G-K) and experiment 2 (L-Q) eyes were exposed to the light-only protocol (30 min of 100 Klux of white light). In experiment 3 (R-W), eyes were exposed to a fluorescein-assisted protocol (2mg of fluorescein i.p., followed 3 min later by a 4 min exposure to 54 Klux of white light).