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. Author manuscript; available in PMC: 2019 Feb 22.
Published in final edited form as: Exp Eye Res. 2017 Mar 20;159:58–68. doi: 10.1016/j.exer.2017.03.009

Figure 3.

Figure 3.

Fundus camera-delivered light induced retinal degeneration leads to more pronounced changes in size and morphology in the RPE cells of SOD1/DJ-1/Parkin-deficient mice (TKO mice) compared to C57BL/6J mice. RPE flat mounts of naive eyes (A,B), eyes treated two weeks earlier with the “light-only” FCD-LIRD protocol (C,D) or the “fluorescein- assisted” (Fl-4@3) FCD-LIRD protocol (E,F) were stained with ZO-1. FCD-LIRD led to increase cell size and increased irregularity in cell shape in both C57BL/6J (A,C,E) and TKO (B,D,F) mice. However, the changes were more prominent in the TKO mice. Scale bar = 50 μm