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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Circ Res. 2019 Feb;124(3):437–450. doi: 10.1161/CIRCRESAHA.118.313129

Figure 8. Combining Aggressive LDL Reduction with Concomitant Anti-Cytokine Therapy.

Figure 8.

The simple two-by-two factorial design trial shown could be used to test both the independent and additive effects of lipid-lowering and inflammation inhibition in the treatment of atherosclerosis.