Table 1.

Common pathways upregulated in aging based on Omics big data

Intestinal immune network for IgA production	Asthma
Natural killer cell-mediated cytotoxicity	Cell adhesion molecules (CAMs)
Rheumatoid arthritis	Staphylococcus aureus infection
TNF signaling pathway	Leishmaniasis
Primary immunodeficiency	Influenza A
Leukocyte transendoghelial migration	Tuberculosis
Complement and coagulation cascdes	Malaria
NF-κB signaling pathway	Chagas disease (American trypanosomiasis
T cell receptor signaling pathway	HTLV-1 infection
Inflammatory bowel disease (IBD)	Systemic lupus erythematosus
Cytokine-cytokine receptor interaction	Antigen processing and presentation
Amoebiasis	Chemokine signaling pathway
Allograft rejection	Phagosome
Viral myocarditis	Hematopoietic cell lineate
Graft-versus-host disease	Prion diseases
Osteoclast differentiation	Type I diabetes mellitus
Pertussis	Autoimmune thyroid disease