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. 2019 Feb 22;14(2):e0212563. doi: 10.1371/journal.pone.0212563

Table 1. Univariable and multivariable generalized estimating equations analysis.

Association with yGR
Univariable Analysis Multivariable Analysis
Coefficient B (standard error) p value Coefficient B (standard error) p value
Age 0.006
(0.0049)
0.199 NA NA
GA area at baseline 0.003
(0.0064)
0.645 NA NA
Distance from fovea -0.036
(0.0511)
0.480 NA NA
FV500 0.023
(0.0062)
<0.001 0.006
(0.0085)
0.510
FV1000 0.015
(0.0126)
0.226 NA NA
FVOUT 0.007
(0.0110)
0.553 NA NA
ΔFV 0.044
(0.0089)
<0.001 0.038
(0.012)
0.001

Results of the generalized estimating equations analysis for the association between geographic atrophy (GA) yearly growth rate (yGR) and age, GA area at baseline, distance from the fovea, percentage of flow voids (FV) in the para-atrophy region (FV500), FV in the peri-atrophy region (FV1000), FV outside the GA (FVOUT), and the difference between FV500 and FV1000 (ΔFV). Only the variables with significant association in the univariable analysis (FV500 and ΔFV) were included in the multivariable statistics.