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. 2019 Feb 22;14(2):e0212808. doi: 10.1371/journal.pone.0212808

Table 2. Cox regression for 28-day mortality in sepsis patients.

Variable HR (95% CI) P value
SOFA score 1.085 (1.011–1.164) 0.023
Underlying disease
 Diabetes mellitus (%) 0.765 (0.412–1.420) 0.396
 Hypertension (%) 0.619 (0.359–1.069) 0.086
Laboratory data
 WBC (×109 /L) 1.050 (1.019–1.083) 0.001
 AST (IU/L) 1.000 (1.000–1.000) 0.068
 ALT (IU/L) 1.000 (1.000–1.000) 0.817
 BUN (mmol/L) 1.046 (1.021–1.072) <0.001
Mononuclear cell mtDNA relative copy number 0.999 (0.998–1.000) 0.017

Note: HR, Hazard ratio; CI, confidence interval; SOFA, sequential organ failure assessment; WBC, white blood cell; AST, aspartate transaminase; ALT, alanine aminotransferase; BUN, blood urea nitrogen;

, laboratory data at presentation in the patients group.