Table 6. The most significant results for HLA-G 3’-UTR and MICA linkage disequilibrium for all groups (Ct, CKD, KTN and KTR).
| Locus 1 | Locus 2 | D’ | LOD | r2 | Variants in cis | |
|---|---|---|---|---|---|---|
| +3010 G>C | +3142 C>G | 1.000 | 7.90 to 39.27 | 0.87 to 1.000 | +3010 C and +3142 G | +3010 G and +3142 C |
| Ins/Del 14bp | +3142 C>G | 0.91 to 1.00 | 5.06 to 18.86 | 0.42 to 0.62 | 14-bp Ins and +3142 G | 14-bp Del and +3142 C |
| MICA-129 Val/Met | MICA A5.1/Wt | 1.000 | 2.22 to 6.71 | 0.19 to 0.27 | MICA-129 Met and MICA Wt | MICA-129 Val and MICA A5.1 |
The significant linkage disequilibrium had an LOD > 3.000 and p < 0.05. LOD: is the log of the likelihood odds ratio. Ct: Control group. CKD: Patients with chronic kidney disease. KTN: Kidney-transplant patients with no rejection. KTR: Kidney-transplant patients who developed episodes of rejection. Wt: wild type, which does not show MICA A5.1 variation. Del: +2960 or 14-bp deletion and Ins: +2960 or 14-bp insertion.