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. 2019 Feb 22;14(2):e0212931. doi: 10.1371/journal.pone.0212931

Table 1. Summary of patient characteristics at the time of kidney transplantation (n = 805) and details concerning immunosuppressive treatments and acute rejection.

Male (%)/Female (%) 492 (61.1)/313 (38.9)
Age at transplantation (years) 51.0 [18.0–83.0]
Primary kidney disease (%)
• Glomerulonephritis 33.9
• Diabetic nephropathy 9.3
• Interstitial nephropathy 36.4
• Vascular nephropathy 7.6
• Other/unknown 12.8
Dialysis duration (months) 33 [0–452]
HD/PD/preemptive transplantation (%) 70.6/19.2/10.2
Transplantation rank ≥ 2 (%) 22.9
Pre-transplant corticotherapy, n = 419 (%) 59.6
Body mass index (kg/m2) 24.7 [13.6–39.1]
Pre-transplant diabetes Type 1/Type 2 1.4/23.9
Dyslipidemia, n = 758 (%) 50.4
Current or former smoker, n = 274 (%) 59.9
Pre-transplant BMD status, n = 707 (%):
• Normal/osteopenia/osteoporosis 31.3/45.8/22.9
Immunosuppressive treatments
• Anti-IL2 receptor antibody/Thymoglobulin (%) 36.7/58.3
• Cyclosporin A/Tacrolimus/mTOR inhibitor (%) 60.7/38.5/1.2
• Total (oral + bolus) corticosteroid dose at M3 (mg) 2075 [500–4790]
• Total (oral + bolus) corticosteroid dose at M12 (mg) 2978 [500–9855]
Delayed graft function (%) 28.5
Acute rejection
• Cumulative incidence at M3/M12/M24 (%) 7.7/16.2/19.8
• Pure TCMR/pure ABMR/mixed (%) 14.9/2.2/2.5

Data are given as percentages or medians [minimum–maximum], as appropriate. HD, hemodialysis; PD, peritoneal dialysis; BMD: bone mineral density; mTOR, mammalian target of rapamycin; n, number of analyzed patients; TCMR, T cell-mediated rejection; ABMR, antibody-mediated rejection.