Table 1. Characteristics of the study population.
| Number of patients (%) | Patients with operation | Patients without operation | Total Cases | Total Controls | ||
|---|---|---|---|---|---|---|
| OP | OP+CTx/RTx | CTx/RTx | Supportive treatment | |||
| Total | 426(14.6) | 296(10.1) | 1405(48.1) | 792(27.1) | 2919(100.0) | 2919(100.0) |
| Males | 313(73.5) | 221(74.7) | 1135(80.8) | 611(77.2) | 2280(78.1) | 2280(78.1) |
| Age at diagnosis | ||||||
| Median (interquartile range) | 64.5(13.0) | 62.0(12.0) | 67.0(12.0) | 74.0(10.0) | 68.0(13.0) | 68.0(13.0) |
| Mean (SD) | 63.7(8.9) | 62.1(8.3) | 65.8(8.6) | 73.2(7.7) | 67.1(9.2) | 67.1(9.2) |
| 40–60 (%) | 127(29.8) | 114(38.5) | 315(22.4) | 43(5.4) | 599(20.5) | 599(20.5) |
| 60–80 (%) | 290(68.1) | 180(60.8) | 1033(73.5) | 580(73.2) | 2083(71.4) | 2083(71.4) |
| 80+ (%) | 9(2.1) | 2(0.7) | 57(4.1) | 169(21.3) | 237(8.1) | 237(8.1) |
| Year at diagnosis | ||||||
| 2004 | 58(13.6) | 30(10.1) | 171(12.2) | 132(16.7) | 391(13.4) | 391(13.4) |
| 2005 | 46(10.8) | 34(11.5) | 195(13.9) | 105(13.3) | 380(13.0) | 380(13.0) |
| 2006 | 44(10.3) | 38(12.8) | 197(14.0) | 105(13.3) | 384(13.2) | 384(13.2) |
| 2007 | 59(13.9) | 54(18.2) | 210(15.0) | 109(13.8) | 432(14.8) | 432(14.8) |
| 2008 | 75(17.6) | 50(16.9) | 195(13.9) | 124(15.7) | 444(15.2) | 444(15.2) |
| 2009 | 72(16.9) | 43(14.5) | 204(14.5) | 98(12.4) | 417(14.3) | 417(14.3) |
| 2010 | 72(16.9) | 47(15.9) | 233(16.6) | 119(15.0) | 471(16.1) | 471(16.1) |
| Smoking statusa | ||||||
| Missing | 5(1.2) | 2(0.7) | 22(1.6) | 17(2.2) | 46(1.6) | 33(1.1) |
| Non-smoker | 216(50.7) | 148(50.0) | 613(43.6) | 404(51.0) | 1381(47.3) | 1801(61.7) |
| Smokerb | 205(48.1) | 146(49.3) | 770(54.8) | 371(46.8) | 1492(51.1) | 1085(37.2) |
| Charlson Comorbidity Index(CCI) score | ||||||
| Median (interquartile range) | 2.0(2.0) | 2.0(2.0) | 2.0(2.0) | 2.0(3.0) | 2.0(2.0) | 2.0(2.0) |
| Mean (SD) | 2.3(1.3) | 2.1(1.2) | 2.3(1.3) | 2.6(1.4) | 2.3(1.3) | 2.1(1.3) |
| 1 | 156(36.6) | 122(41.2) | 520(37.0) | 219(27.7) | 1017(34.8) | 1264(43.3) |
| 2 | 116(27.2) | 81(27.4) | 398(28.3) | 227(28.3) | 822(28.2) | 799(27.4) |
| 3 | 76(17.8) | 55(18.6) | 224(15.9) | 146(18.4) | 501(172) | 394(13.5) |
| 4 | 40(9.4) | 20(6.8) | 134(9.5) | 88(11.1) | 282(9.7) | 235(8.1) |
| 5 | 38(8.9) | 18(6.1) | 129(9.2) | 112(14.1) | 297(10.2) | 227(7.8) |
| Income levelc | ||||||
| 1 | 51(12.0) | 40(13.5) | 233(16.6) | 195(24.6) | 519(17.8) | 523(17.9) |
| 2 | 64(15.0) | 46(15.5) | 255(18.2) | 163(20.6) | 528(18.1) | 468(16.0) |
| 3 | 54(12.7) | 44(14.9) | 150(10.7) | 62(7.8) | 310(10.6) | 359(12.3) |
| 4 | 96(22.5) | 70(23.7) | 360(25.6) | 151(19.1) | 677(23.2) | 653(22.4) |
| 5 | 161(37.8) | 96(32.4) | 407(29.0) | 221(27.9) | 885(30.3) | 916(31.4) |
OP = surgery; OP+CTx/RTx = surgery with anti-cancer drugs or radiotherapy; CTx/RTx = anti-cancer drugs or radiotherapy
a The most recent health screening results based on the time of diagnosis
b Current smoker or ex-smoker
c 1: Medicaid & National Health Insurance (NHI) self-employed/employee subscriber Low; 2: NHI self-employed subscriber Medium; 3: NHI self-employed subscriber High; 4: NHI employee subscriber Medium; 5: NHI employee subscriber High