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. 2019 Feb 11;15(2):e1006771. doi: 10.1371/journal.pcbi.1006771

Fig 5. The geometrical rule reproduces the complete sequence of events up to the 16C stage.

Fig 5

Results of recursively applying the rule from an initial truncated sphere (1C, Top). The model was run 50 times at each generation, with volume-ratio ρ* set to 0.5 (1C-2C and 2C-4C transitions), 0.45 (4C-8C) and 0.33 (8C-16C). The best simulation according to the rule was selected as input for the next generation. Cellular patterns observed on real embryos from the the corresponding stages are shown for comparison.