Fig 9. LAVs competent for myeloid cell replication induce greater systemic cytokine responses.

CD-1 mice were infected with equal genomes of the indicated LAV and at 24 hours post infection, serum was collected for Luminex analysis. Asterisks above each box and whisker plots indicate significant difference compared to mock. Bars indicate significant differences between triple and quadruple mutant LAVs only. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001, by one-way analysis of variance with Turkey’s multiple-comparison test. N = 4 mice.