FIG 7.

Analysis of IL-1β release in BMDMs. LPS-primed BMDMs were left uninfected or infected with indicated Y. pseudotuberculosis 32777 ΔyopM strains for 90 min or 180 min. Supernatants were collected and analyzed by ELISA to detect the release of IL-1β. Data represent average values ± the standard errors of the means from three independent experiments. Significant differences comparing the results of the same strains or different strains at the two time points were determined by two-way ANOVA. ns, not significant; **, P < 0.01.