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. 2019 Feb 21;87(3):e00776-18. doi: 10.1128/IAI.00776-18

TABLE 1.

Functional categories of indole-responsive genes

Functional group No. of genes
Upregulated Downregulated Total
Amino acid biosynthesis 4 0 4
Biosynthesis of cofactors, prosthetic groups, and carriers 0 1 1
Cell envelope 6 2 8
Cellular processes 2 1 3
Conserved, hypothetical, and unknown 23 22 45
DNA replication, recombination, and repair 0 1 1
Metabolism 21 2 23
Pathogenesis 2 21 23
Purines, pyrimidines, nucleosides, and nucleotides 1 0 1
Protein fate 0 5 5
Regulatory functions 3 6 9
Transport and binding proteins 12 8 20
Total 74 69 143