Table 2:

Association between nuclear and cytoplasmic survivin and breast cancer recurrence from a population-based case control study of 1312 women age 35–69, diagnosed with Stage I–III breast cancer between 1985–2001, and registered with the Danish Breast Cancer Group.

	ER+/TAM+			ER−/TAM−
Survivin Expression	Case	Control	Adjusted OR (95%CI)	Case	Control	Adjusted OR (95%CI)
Nuclear
>75th%tile	82	82	0.91 (0.62, 1.33)	76	68	1.27 (0.77, 2.09)
50th-75th %tile	94	84	1.14 (0.80, 1.64)	43	49	0.89 (0.52, 1.53)
<50th %tile	236	245	Reference	127	126	Reference
≥50th %tile	176	166	1.03 (0.76, 1.39)	119	117	1.09 (0.72, 1.66)
<50th %tile	236	245	Reference	127	126	Reference
Cytoplasmic
>75th%tile	103	108	0.94 (0.66, 1.34)	61	61	1.13 (0.69, 1.85)
50th-75th %tile	112	104	1.11 (0.78, 1.56)	67	64	1.04 (0.64, 1.67)
<50th %tile	197	199	Reference	118	118	Reference
≥50th %tile	215	212	1.02 (0.77, 1.36)	128	125	1.08 (0.73, 1.61)
<50th %tile	197	199	Reference	118	118	Reference
Joint
Yes	412	411	1.13 (0.83, 1.54)	246	243	1.20 (0.76, 1.87)
No	63	76	Reference	25	28	Reference
CNR
≥5	73	69	1.11 (0.70, 1.77)	33	19	2.48 (1.15, 5.31)
<5	103	97	Reference	86	98	Reference