Table 1.
Baseline Demographic and Clinical Characteristics of the Study Patients
| Characteristic | Atypical Antipsychotic–Treated Group (n=21) | Lithium- or Lamotrigine-Treated Group (n=16) | p Value |
|---|---|---|---|
| Sex | |||
| Male | 12 (57) | 9 (56) | 0.96 |
| Female | 9 (43) | 7 (44) | |
| Race | |||
| Caucasian | 16 (76) | 14 (88) | 0.35 |
| Age (yrs) | 54 ± 10 | 50 ± 15 | 0.31 |
| Education (yrs) | 15 ± 2.2 | 17 ± 3.4 | 0.08 |
| Diagnosis | |||
| Bipolar I | 9 (43) | 10 (63) | 0.02 |
| Bipolar II | 3 (14) | 6 (37) | |
| Schizoaffective Disorder | 5 (24) | 0 (0) | |
| Schizophrenia | 4 (19) | 0 (0) | |
| No. of Psychiatric Hospitalizations |
6 ± 8.1 | 3 ± 3.5 | 0.15 |
| Anthropometric Measurements | |||
| Body Mass Index (kg/m2) | 30.6 | 31.1 | 0.7 |
| Waist:Hip ratio | 0.98 | 1 | 0.25 |
| Metabolic syndrome | 8 (38) | 3 (19) | 0.2 |
| Activity Scorea | 4891 | 9774 | 0.28 |
| Smoker | 5 (24) | 5 (31) | 0.89 |
| Concomitant Medications | |||
| Antidepressants | 9 (43) | 12 (75) | 0.051 |
| Benzodiazepines | 5 (24) | 4 (25) | 0.9 |
| Medication for Hypertension | 12 (57) | 4 (25) | 0.051 |
| Medication for Diabetes Mellitus | 2 (10) | 0 (0) | 0.2 |
| Medication for Hyperlipidemia | 10 (48) | 2 (13) | 0.02 |
| Nutrition | |||
| Total (Kcal/day) | 2183 | 2181 | 0.99 |
| Protein (g/day) | 89 | 85 | 0.77 |
| Fat (g/day) | 92 | 83 | 0.41 |
| Carbohydrates (g/day) | 254 | 254 | 0.99 |
| Fiber (g/day) | 20 | 18 | 0.6 |
| HEI-2010c | 56 | 50 | 0.26 |
Data are no. (%) of patients, mean ± SD values, or mean values.
a
Activity Score = Global Physical Activity Questionnaire.
b
Atypical antipsychotics = clozapine, olanzapine, risperidone, quetiapine, ziprasidone.
c
Healthy Eating Index–2010