Table 2.
Intention-to-treat analysis for participants with data receiving either Mindfulness-based Stress Reduction (MBSR) or Education Control.
| Baseline Levels | Immediately Post-intervention | 12-mos Follow-up | Intervention Effects (Δ baseline to immediately post)a | 12-mos Follow-up Effects ( Δ baseline to 12-mos Follow-up)a | |||||
|---|---|---|---|---|---|---|---|---|---|
| MBSR n=33 | MBSR n=31 | MBSR n=29 | MBSR n=31 | MBSR n=29 | |||||
| EDU n=29 | EDU n=28 | EDU n=27 | EDU n=28 | EDU n=27 | |||||
| Secondary Measures | mean ± sd | mean change (95% CI) | mean change (95%CI) | F | p | ES (95% CI) | F | p | ES (95% CI) |
| Perceived Stress Scale | 1.10 | 0.30 | −0.21 (−.72 to 0.30) | 1.53 | 0.22 | −0.25 (−0.78 to 0.28) | |||
| MBSR | 17.76 ± 6.06 | −5.29 (−2.46 to −8.12) | −4.34 (−1.96 to −6.73) | ||||||
| Education | 18.0 ± 5.71 | −3.89 (−1.9 to −5.86) | −2.74 (−0.14 to −5.34) | ||||||
| SF-36 Emotional Wellbeing | 0.50 | 0.48 | 0.15 (−0.36 to 0.66) | 0.36 | 0.55 | 0.09 (−0.44 to 0.61) | |||
| MBSR | 63.39 ± 16.97 | 11.74 (4.50 to 18.98) | 6.76 (−1.06 to 14.58) | ||||||
| Education | 63.31 ± 16.25 | 9.14 (3.36 to 14.93) | 5.04 (−1.92 to 12.00) | ||||||
| PROMIS Anxiety | 2.41 | 0.13 | −0.48 (−0.99 to 0.04) | 0.01 | 0.91 | 0.01 (−0.52 to 0.53) | |||
| MBSR | 59.81 ± 6.76 | −6.26 (−3.53 to −9.0) | −5.36 (−2.63 to −8.09) | ||||||
| Education | 58.06 ± 6.04 | −3.26 (−1.45 to −5.08) | −5.40 (−2.47 to −8.32) | ||||||
| PROMIS Depression | 1.84 | 0.18 | −0.39 (−0.90 to 0.13) | 0.34 | 0.56 | −0.16 (− 0.68 to 0.37) | |||
| MBSR | 55.21 ± 6.47 | −4.77 (−2.15 to −7.38) | −4.49 (−1.48 to −7.50) | ||||||
| Education | 54.28 ± 5.51 | −2.47 (−0.81 to −4.13) | −3.33 (−0.72 to −5.94) | ||||||
| PROMIS Fatigue | 0.71 | 0.40 | −0.18 (−0.69 to 0.33) | 0.8 | 0.37 | −0.21 (−0.74 to 0.31) | |||
| MBSR | 60.74 ± 8.29 | −4.57 (−1.49 to −7.64) | −4.99 (−1.94 to −8.04) | ||||||
| Education | 60.23 ± 7.63 | −3.28 (−1.18 to −5.37) | −3.55 (−1.61 to −5.49) | ||||||
| PROMIS Pain Interference | 0.07 | 0.79 | −0.03 (−0.54 to 0.48) | 3.03 | 0.09 | 0.45 (−0.08 to 0.98) | |||
| MBSR | 55.48 ± 10.47 | −2.21 (0.02 to −4.45) | 1.09 (3.70 to −1.51) | ||||||
| Education | 55.17 ± 9.10 | −1.96 (1.49 to −5.40) | −1.95 (0.65 to −4.55) | ||||||
| Resilience | 1.14 | 0.30 | 0.35 (−0.16 to 0.87) | 0.72 | 0.40 | 0.29 (− 0.24 to 0.82) | |||
| MBSR | 63.76 ± 9.15 | 8.10 (4.29 to 11.91) | 7.55 (2.14 to 12.97) | ||||||
| Education | 67.10 ± 12.2 | 4.61 (0.99 to 8.23) | 3.93 (−0.18 to 8.03) | ||||||
| PASAT 3' | 0.30 | 0.59 | 0.03 (−0.49 to 0.54) | 0.3 | 0.59 | 0.12 (−0.41 to 0.65) | |||
| MBSR | 44.67 ± 11.07 | 2.51 (0.84 to 4.19) | 2.59 (−1.06 to 6.24) | ||||||
| Education | 39.93 ± 10.38 | 2.39 (0.38 to 4.41) | 1.56 (−1.59 to 4.70) | ||||||
Acronyms: EDU (education control); ES (effect size); PASAT (Paced Auditory Serial Addition Test); PROMIS (Patient Reported Outcomes Information System); CAT (Computerized Adaptive Test)
a
ANCOVA adjusting for baseline levels. F statistic and p value are for the group effect. ES is Cohen’s d comparing changes from baseline between groups.
For PROMIS surveys, higher scores indicate more of the construct being measured. For SF-36 subscales, higher scores indicate better health. PASAT scores are number of correct answers out of 60, higher scores are better.