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Ti-Tregs preferentially express T-bet and CXCR3. CD4+Foxp3+ T cells in TdLN and tumor tissue from B16F10 s.c. tumor-bearing mice were analyzed by FACS at 15 d after tumor inoculation. (A) The histograms and geometric mean fluorescence intensity (MFI) for indicated transcription factors and (B) chemokine receptors. The graphs show means ± SEM (**P < 0.01 and ***P < 0.001). Data are representative of two independent experiments (n = 3–4).
