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Summary of GPR68 functions in cancer cells and other cells in the tumor microenvironment (TME). GPR68 is expressed on a variety of cells in the TME, each of which has responses to GPR68 activation, as indicated on the figure. * GPR68 has not as-yet been directly shown on tumor endothelial cells, but based on data for vascular endothelial cells are likely to be present in tumors.
