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Diagrammatic representation of tocotrienols-mediated apoptosis activation. Tocotrienols can regulate both intrinsic and extrinsic apoptotic pathways via mitochondrial membrane potential depolarization, cyt. C (cytochrome complex) release, activation of caspase cascade and also modulation of Bcl-2 (B-cell lymphoma 2) as well as Bax expression.
