Table 1.
Characteristics of patients at baseline.
| Parameter | All Participants | Baseline eGFR Category | Hemodialysis | |||
|---|---|---|---|---|---|---|
| G1 | G2 | G3a–G3b | G4–G5 | |||
| n | 189 | 21 | 123 | 34 | 8 | 3 |
| Age (years) | 57.8 (10.5) | 52.6 (9.8) | 55.9 (9.3) | 65.5 (9.7) | 64.6 (12.8) | 67.7 (12.5) |
| Sex, Men | 147 (77.8) | 16 (76.2) | 98 (79.7) | 25 (73.5) | 7 (87.5) | 1 (33.3) |
| BMI (kg/m2) | 26.0 (3.5) | 26.6 (4.6) | 26.1 (3.4) | 25.8 (2.5) | 26.0 (2.3) | 23.4 (7.3) |
| Type 2 diabetes | 70 (37.0) | 10 (47.6) | 39 (31.7) | 16 (47.1) | 4 (50.0) | 1 (33.3) |
| Hypertension | 101 (53.4) | 8 (38.1) | 57 (46.3) | 26 (76.5) | 7 (87.5) | 3 (100) |
| Fatty liver | 140 (74.1) | 19 (90.5) | 91 (74.0) | 26 (76.5) | 4 (50.0) | 0 |
| Use of a statin | 108 (57.1) | 11 (52.4) | 77 (62.6) | 18 (52.9) | 2 (25.0) | 0 |
| TG (mmol/L) | 2.82 (0.88) | 2.94 (1.03) | 2.80 (0.89) | 2.88 (0.86) | 2.72 (0.47) | 2.47 (0.53) |
| HDL-C (mmol/L) | 1.18 (0.27) | 1.24 (0.36) | 1.19 (0.24) | 1.19 (0.31) | 0.87 (0.22) | 1.12 (0.42) |
| LDL-C (mmol/L) | 3.09 (0.82) | 3.20 (0.88) | 3.08 (0.78) | 2.96 (0.72) | 3.42 (1.18) | 3.45 (2.09) |
| Serum creatinine (mg/dL) | 1.05 (1.00) | 0.62 (0.10) | 0.82 (0.12) | 1.09 (0.25) | 3.23 (1.30) | 7.35 (1.68) |
| eGFR (mL/min/1.73 m2) | 68.6 (20.3) | 99.6 (8.0) | 72.9 (8.5) | 51.1 (7.0) | 18.2 (6.9) | 5.6 (1.4) |
| HbA1c (%) | 6.3 (0.9) | 6.5 (1.1) | 6.2 (0.8) | 6.6 (1.0) | 6.1 (0.4) | 6.7 (1.9) |
Data are presented as means (SD) for continuous parameters and n (%) for categorical parameters. Baseline eGFR categories are as follows: G1, eGFR ≥90 mL/min/1.73 m2; G2, eGFR ≥60 and <90 mL/min/1.73 m2; G3a–G3b, eGFR ≥30 and <60 mL/min/1.73 m2; G4–G5, eGFR <30 mL/min/1.73 m2. BMI, body mass index; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c; SD, standard deviation.