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. 2019 Jan 29;20(3):572. doi: 10.3390/ijms20030572

Figure 9.

Figure 9

IL-2 and IFN-γ secretion by T cells in response to co-culture with different tumor cell to T cell ratio. (A) TE-13 co-culture with T cells reduced IL-2 secretion, (B) A549 co-culture with T cells significantly reduced IL-2 secretion, (C) MDA-MB-231co-culture with T cells also significantly reduced IL-2 secretion; T cell culture without tumor cells was used as a negative control. Moreover, the same tumor cell lines at same mixing ratios with T cells also showed a significant reduction of IFN-γ levels in the culture systems as illustrated in (D–F). There were three replicates for each experimental condition. * p < 0.05, ** p < 0.01 and *** p < 0.001, compared with the control group of T cells.