4EBP1	Eukaryotic translation initiation factor 4E binding protein 1
AEs	Adverse events
AMPK	AMP kinase
AMPKβ	AMP activated protein kinaseβ
ATP	Adenosine Tri-Phosphate
BBN	N-butyl-N-(4-hydroxybutyl) nitrosamine
Bgff	Basic fibroblast growth factor
CBR	Clinical benefit rate
ccRCC	Clear cell renal cell carcinoma
chRCC	Chromophobe renal cell carcinoma
CRC	Colorectal cancer
CRPC	Castration-resistance prostate cancer
CSC	Cancer stem cells
CT	Chemotherapy
DAP1	Death-associated protein 1
DCR	Disease control rate
DEP	EGL-10 and Pleckstrin
DEPTOR	DEP domain-containing mTOR-interacting protein
EBV	Epstein-Barr virus
EGFR	Epidermal Growth Factor Receptor
eIF-3	Eukaryotic initiation factor-3
eIF-4E	Eukaryotic translation Initiation Factor
EMT	Epithelial mesenchymal transition
ERKs	Extracellular signal-regulated kinases
FDA	Food and Drug Administration
FKBP12	FK506 Binding Protein 12
FoxO	Forkhead box family transcription factors
GC	Gastric cancer
Grb10	Growth factor receptor-bound protein 10
HER2	Human epidermal growth factor receptor 2
HIF-1α	Hypoxia-inducible factor 1α
HNSCC	Head and neck squamous cell carcinoma
HPV	Papilloma virus
HR	Hormone Receptor
IGFR	Insulin growth factor receptor
IRS	Insulin receptor substrate
LAR	Long-acting release
MAPK	Mitogen activated protein kinase
MEK	Mitogen-activated protein kinase kinase
MIUBCs	Muscle-invasive UBCs
mLST8	Mammalian lethal with SEC13 protein 8
mRCC	Metastatic renal cell carcinoma
mSIN1	Mammalian stress-activated protein kinase interacting protein 1
mTOR	The mammalian or mechanistic target of rapamycin
mTORC	mTOR complex
NDRG1	N-myc Downstream-Regulated Gene 1 protein
NF-κB	Nuclear factor-κB
NMIUBCs	Non-muscle-invasive UBCs
NSCLC	Non-small cell lung cancer
OS	Overall survival
p-Akt	Phosphor-protein kinase B
PCa	Prostate cancer
PDGF	Platelet-derived growth factor
PDK1	Phosphoinositide-dependent Kinase 1
PFS	Progression free survival
PI3K	Phosphoinositide 3-kinase
PIKK	Phosphoinositide 3-kinase related protein kinase
PIP3	Phosphatidylinositol (3, 4, 5)-triphosphate
PKA	cAMP-dependent protein kinase
PKC	Protein kinase C
PKG	cGMP-dependent protein kinase
p-mTOR	Phosphorylated-mTOR
PP2A	Protein phosphatase 2A
PRAS40	Proline-rich substrate of 40 kDa
PRCC	Papillary renal cell carcinoma
Protor-1/2	Protein observed with RICTOR 1/2
PRR 5	Proline-rich protein 5
p-S6K1	p70 ribosomal S6 Kinase
PTEN	Phosphatase and tensin homolog on chromosome 10
RAPTOR	Regulatory-associated protein of mTOR
RCC	Renal cancer
REDD1	DNA damage and development 1
RHEB	Ras homolog enriched in brain
RICTOR	Rapamycin-insensitive companion of mTOR
RR	Radioresistance
RSK	Ribosomal protein S6 kinase
S6K	S6 kinase
S6RP	S6 ribosomal protein
SCLC	Small cell lung cancinoma
SGK	Serum glucose kinase
SNP	Single-nucleotide polymorphisms
SQCLC	Squamous cell lung carcinoma
SREBP	Sterol regulatory element-binding protein
SRE-BP1	Sterol regulatory element-binding protein 1
STAT	Signal transducer and activator of transcription
STK11	Serine threonine kinase 11
TCGA	The cancer genome atlas
Tel2	Telomere maintenance 2
TFEB	Transcription factor transcription factor EB
TNBC	Triple-negative breast cancer
TSC	Tuberous sclerosis complex
Tti1	Tel2-interacting protein 1
TTP	Time to progression
UBC	Urinary bladder cancer
ULK1	UNC-5 Like autophagy activating Kinase 1
VEGF	Vascular endothelial growth factor
WIPI2	WD repeat domain phophoinositide-interacting protein 2