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F145 diffusion into the mature S. aureus biofilm. The 24 h old biofilm was treated with F145 for 1 h and analyzed with confocal laser scanning microscopy using a single-channel mode. (a) X; Y orientation of the biofilm; (b) Z-stack of the biofilm; (c) 3D-model of the biofilm. The scale bars indicate 10 μm.
