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. 2019 Jan 30;20(3):588. doi: 10.3390/ijms20030588

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Dose–efficiency curves (number of γH2AX labelling tags vs. dose counted by SMLM). For the irradiated SkBr3 cell nuclei without Au-NP incorporation (left graph, a linear increase (red fit curve) can be observed at doses between 0 and 2 Gy. This was compatible to the blue linear fitting curve for irradiated SkBr3 cell nuclei with Au-NP incorporation (right graph. For the higher dose values, an exponential growth (red fit curve) or quadratic increase could be fitted to the values. (black square: mean value; error bar: standard deviation)