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Sequence of the CS chain of bikunin as proposed by Ly et al. 2011 [11] (a) and Lord et al. 2013 [10] (b). The KPI SPI domains are shown in (b). and the attached N-glycan chain of KPI-1. The over-sulfated CS-D disaccharide is shown which forms part of the MO-225 epitope embedded in the CS-A chain of bikunin. Arrangement of sulfated, disulfated and non-sulfated regions of the CS chain of bikunin are shown. The arrow shows the Asparagine residue on Kunitz domain 1.
