Table 1.
Association of MDM2 SNP309 genotypes and alleles with breast cancer risk.
| Genotypes/Alleles | All subjects | SNP285GG Subjects | All Subjects | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | Unadjusted | Adjusted for SNP285 | |||||||
| OR | 95% CI | p-Value | OR | 95% CI | p-Value | OR | 95% CI | p-Value | |
| GG vs. TT | 1.36 | 0.81–2.28 | 0.278 | 1.32 | 0.77–2.25 | 0.321 | 1.33 | 0.79–2.24 | 0.308 |
| GG vs. TG | 1.50 | 0.90–2.52 | 0.117 | 1.47 | 0.87–2.54 | 0.169 | 1.49 | 0.90–2.50 | 0.116 |
| GG vs. TG + TT | 1.43 | 0.88–2.32 | 0.143 | 1.39 | 0.84–2.31 | 0.191 | 1.42 | 0.87–2.31 | 0.152 |
| TG vs. TT | 0.91 | 0.65–1.27 | 0.579 | 0.89 | 0.63–1.26 | 0.513 | 0.89 | 0.63–1.25 | 0.518 |
| TG + GG vs. TT | 0.99 | 0.72–1.36 | 0.942 | 0.97 | 0.70–1.34 | 0.856 | 0.97 | 0.70–1.34 | 0.856 |
| G vs. T | 1.08 | 0.86–1.36 | 0.507 | 1.06 | 0.84–1.35 | 0.620 | 1.07 | 0.85–1.35 | 0.563 |
Analyses of breast cancer cases vs. controls of the indicated SNP309 genotypes or alleles are shown. Analyses were performed in all subjects or subjects with the SNP285 genotype GG, unadjusted or adjusted for SNP285 genotype as indicated. OR, odds ratios; 95% CI, 95% confidence intervals.