| ANOVA | one-way analysis of variance |
| AFM | atomic force microscope |
| AUC | area under the drug concentration-time curve |
| BA | bioavailability |
| Caco-2 | human epithelial colorectal adenocarcinoma cell line |
| CavME | caveolae-dependent endocytosis |
| CME | clathrin-dependent endocytosis |
| COX | cyclooxygenase |
| DMEM | Dulbecco’s Modified Eagle Medium |
| DMSO | dimethyl sulfoxide |
| HPβCD | 2-hydroxypropyl-β-cyclodextrin |
| DDS | drug delivery systems |
| IND-MPs | oral formulation containing indomethacin microparticles |
| IND-NPs | oral formulation containing indomethacin nanoparticles |
| IND-solution | liquid indomethacin |
| MP | macropinocytosis |
| MC | methylcellulose |
| NO | nitric oxide |
| NSAID | non-steroidal anti-inflammatory drug |
| PG | prostaglandin |
| S.D. | standard deviation |
| S.E. | standard error |
| TER | transepithelial electrical resistance |