Figure 1.

Olanzapine caused weight gain. During a course of 14 days, body weight and food intake were recorded over time. Daily changes in body weight (A), average body weight gain (B), and food intake (C) were summarized and depicted. At the end of the experiments, the weight of excised white adipose tissues (D), liver (E), and gastrocnemius (F) was measured. (G) The excised liver and perirenal white adipose tissues were subjected to histological examination. Representative photomicrographs of Hematoxylin and Eosin (H&E) stain are shown. * p < 0.05 vs. control, n = 10. Scale Bar: 0.1 mm. Arrows indicate a deposition of lipid droplets.