Figure 2.

Olanzapine caused a metabolic disturbance. At the end of the experiments, serum samples were subjected to analyses for the measurement of aspartate aminotransferase (AST) (A), alanine aminotransferase (ALT) (B), triglycerides (C), total cholesterol (D), fasting glucose (E), and insulin (F). The value of Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) is depicted in (G). (H) Proteins were extracted from the excised liver tissues and subjected to Western blotting with indicated antibodies. Representative blots are shown, and the quantitative data are depicted. * p < 0.05 vs. control, n = 10.