Figure 6.

Chromium improved olanzapine-induced metabolic disturbance. At the end of the experiments, tissue lipids were homogenized and extracted from livers and subjected to an enzymatic assay for the measurement of hepatic triglycerides and cholesterol (A). Serum samples were subjected to analyses for the measurement of lipids (B), fasting glucose (C), and insulin (D). The value of HOMA-IR is depicted in (E). (F) Proteins were extracted from the excised liver tissues and subjected to Western blotting with indicated antibodies. Representative blots are shown, and the quantitative data are depicted. (G) Serum samples were subjected to analyses for the measurement of IL-6. * p < 0.05 vs. control and # p < 0.05 vs. olanzapine control, n = 10.