Table 2.

Hair-related important DEGs between transgenic sheep and wild-type siblings.

Gene Name	Description	Reference
β-catenin	β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin	[7]
MMP-7	MMP-7 or matrilysin (β-catenin target gene) is expressed in hair placode keratinocytes	[11]
FN1	β-catenin target gene	[12]
KRT79	Keratin 79 identifies a novel population of migratory epithelial cells that initiate hair canal morphogenesis and regeneration	[13]
KRT2.11	KRT2.11 transcripts are present in wool follicle RNA and are expressed in follicle cortical keratinocytes located above the dermal papilla	[14]
KRT8	KRT8 is an epithelial marker	[15]
KRT71	Mutations in KRT71 are observed in mice, rats, and dogs and are linked to a wavy coat phenotype	[16]
KRT5	KRT5 is a marker of basal and undifferentiated keratinocytes and is increased in the epidermis of alopecic mice	[17]
KRTAP1-1	The ovine KRTAP1-4 gene is clustered with the KRTAP1-1 and KRTAP1-3 genes on chromosome 11 and appears to be associated with wool staple	[18]
KRT25	A homozygous missense variant in type I keratin KRT25 causes autosomal recessive woolly hair	[19]