| 2D | two-dimensional |
| 3D | three-dimensional |
| BMI | body mass index |
| col I/II | collagen type I/II |
| DM | diabetes mellitus |
| FBS | foetal bovine serum |
| FDA | fluorescein diacetate |
| hAC | human articular chondrocytes |
| HBSS | Hank’s balanced salt solution |
| HG | hyperglycemia |
| HI | hyperinsulinemia |
| IL | interleukin |
| MMPs | matrix metalloproteinases |
| NG | normoglycemia |
| OA | osteoarthritis |
| PBS | phosphate buffered saline |
| PFA | paraformaldehyde solution |
| PG | proteoglycan |
| PGE2 | Prostaglandin E2 |
| PI | propidium iodide |
| ROS | reactive oxygen species |
| RT | room temperature |
| SD | standard deviation |
| STAT | Signal Transducer and Activator of Transcription |
| T2DM | type 2 diabetes mellitus |
| TE | TRIS EDTA buffer |
| TBS | TRIS buffered saline |
| TBST | TRIS-buffered saline with Triton X 100 |