Table 2.

List of pathways associated with diseases and disorders, molecular and cellular functions, physiological system development and functions in normozoospermic and asthenozoospermic testicular cancer patients.

Groups	Normozoospermic TC			Asthenozoospermic TC
Category	Pathways	p-Value	Number of DEPs	Pathways	p-Value	Number of DEPs
Disease and disorders	Inflammatory response	2.36 × 10−14–6.15 × 10−7	46	Inflammatory Response	1.96 × 10−22–2.37 × 10−3	84
	Cancer	4.65 × 10−11–7.06 × 10−6	142	Cancer	3.9 × 10−11–2.19 × 10−3	228
	Organism injury and abnormalities	4.65 × 10−11–7.06 × 10−6	142	Organism injury and abnormalities	3.9 × 10−11–2.39 × 10−3	232
	Reproductive system disease	1.3 × 10−10–7.06 × 10−6	104	Metabolic disease	1.2 × 10−10–2.36 × 10−3	90
	Neurological disease	3.21 × 10−10–7.06 × 10−6	47	Gastrointestinal disease	2.02 × 10−9–2.13 × 10−3	214
Molecular and cellular functions	Cellular compromise	2.36 × 10−14–2.45 × 10−7	30	Cellular compromise	1.96 × 10−22–1.88 × 10−3	59
	Protein synthesis	1.06 × 10−11–2.54 × 10−6	39	Protein synthesis	3.16 × 10−14–2.36 × 10−3	74
	Post-translational modification	2.17 × 10−11–6.41 × 10−10	18	Protein degradation	3.93 × 10−14–2.36 × 10−3	39
	Protein degradation	2.17 × 10−11–6.41 × 10−10	26	Cellular assembly and organization	8.2 × 10−11–2.36 × 10−3	46
	Lipid metabolism	4.3 × 10−11–6.79 × 10−6	26	Post-translational modification	2.08 × 10−10–2.36 × 10−3	52
Physiological system development and functions	NA	NA	NA	Reproductive system development and function	4.14 × 10−10–2.05 × 10−3	40
	NA	NA	NA	Hematological system development and function	3.85 × 10−7–2.37 × 10−3	38
	NA	NA	NA	Immune cell trafficking	3.85 × 10−7–2.37 × 10−3	39
	NA	NA	NA	Organ development	9.75 × 10−6–2.4 × 10−3	36
	NA	NA	NA	Cardiovascular system development and function	2.62 × 10−5–2.23 × 10−3	40