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. 2019 Jan 24;20(3):502. doi: 10.3390/ijms20030502

Figure 8.

Figure 8

Post-injury administration of 3,6′-DT at 5 h after TBI significantly reduced the elevated tissue levels of inflammatory cytokine proteins measured at 8 h. (A) TNF-α, (B) IL-1β, and (C) IL-6 protein levels in TBI + Veh rats were significantly elevated in the ipsilateral cortex at 8 h after injury. Administration of 3,6′-DT mitigated the rise in these three cytokine levels, which reached statistical significance for TNF-α, and IL-1β, but not IL-6. Data are presented as mean ± S.E.M. (n = 5 in each group). *** p < 0.001 compared with the Sham group. # p < 0.05, ## p < 0.01, ### p < 0.001 compared with the TBI + Veh group.