Table 3.
The detailed disease activity index (DAI) score and description on days 4–8 during colitis induced with 2.5% dextran sodium sulfate solution
| Time | Group | S1 | S2 | S3 | DAI | Description |
|---|---|---|---|---|---|---|
| Day 4 | Con | 0 | 5 | 0 | 0.28 ± 0.19 | 2×semiloose (++), 1×semiloose (+) |
| Ganoderma lucidum polysaccharide (GLP) | 0 | 1 | 0 | 0.06 ± 0.14 | 1×semiloose (+) | |
| Day 5 | Con | 0 | 9 | 0 | 0.50 ± 0.17 | 3×semiloose (++), 1×loose (+) |
| GLP | 0 | 6 | 0 | 0.33 ± 0.33 | 1×semiloose (++), 1×semiloose (+), 1×loose (+) | |
| Day 6 | Con | 0 | 14 | 3 | 0.94 ± 0.36 | 2×loose (+) + fecal occult blood (+),1×loose (+), 1×semiloose (++) + fecal occult blood (+), 1×semiloose (++), 1×semiloose (+) |
| GLP | 0 | 14 | 1 | 0.83 ± 0.28 | 1×loose (+) + fecal occult blood (+), 1×loose (+), 4×semiloose (++) | |
| Day 7 | Con | 0 | 20 | 11 | 1.72 ± 0.49 | 2×loose (++) + hematochezia (+), 1×loose (+) + fecal occult blood (++), 3×loose (+) + fecal occult blood (+) |
| GLP | 0 | 18 | 5 | 1.28 ± 0.25 | 1×loose (+) + fecal occult blood (++), 3×loose (+) + fecal occult blood (+), 2×loose (+) | |
| Day 8 | Con | 4 | 24 | 24 | 2.89 ± 0.17 | 4×loose (++) + hematochezia (++) + 1–5% body weight decreasing, 2×loose (++) + hematochezia (++) |
| GLP | 0 | 19 | 5 | 1.33 ± 0.30* | 1×loose (+) + fecal occult blood (++), 1×loose (++) + fecal occult blood (+), 2×loose (+) + fecal occult blood (+), 2×loose (+) |
Note: DAI was calculated by using the equation *, significant difference was found when compared with Group Con on the same day (P < 0.05). S1, the total score of the body weight decrease rate; S2, the total score of the fecal property; S3, the total score of hematochezia status. The detailed criteria for the scoring are referred to in Table 2.