Table 3.
Linear regression analysis of change in R1 (ΔR1) versus change in R2* (ΔR2*) at scan 1post (immediately post-USPIO) and scan 2 (24–30 h post-USPIO). Changes are calculated relative to scan 1pre (pre-USPIO) values. Statistically significant associations are indicated by * (p < 0.05), ** (p < 0.01) and *** (p < 0.001).
| ROI | Scan 1post | Scan 2 | ||||
|---|---|---|---|---|---|---|
| β0 (s−1) | β1 | R 2 | β0 (s−1) | β1 | R 2 | |
| WM | 2.6 | 14.2 | 0.18 | 2.5 | 33.4 | 0.61 ** |
| GM | 4.7 | 14.9 | 0.06 | 1.7 | 69.2 | 0.70 *** |
| WMH | 2.1 | 18.7 | 0.75 * | 2.4 | 25.3 | 0.73 *** |
| SL | 1.8 | 47.2 | 0.34 | 1.3 | 56.9 | 0.64 ** |
β0: intercept, β1: slope, WM: normal-appearing white matter, GM: grey matter, WMH: white matter hyperintensities, SL: stroke lesion.