ER | Endoplasmic reticulum |
HCC | Hepatocellular carcinoma |
UPR | Unfolded protein response |
PERK | Protein kinase RNA (PKR)-like ER kinase |
IRE1 | Inositol-requiring protein 1 |
ATF6 | Activating transcription factor 6 |
ATF4 | Activating transcription factor 4 |
GRP78/Bip | 78-kDa glucose regulated protein/binding immunoglobulin protein |
COX-2 | Cyclooxygenase-2 |
NFκB | Nuclear factor-κB |
OBI | Occult HBV infection |