Fig. 3.
Associations between cerebral soluble Aβ and key cytokines in ADtg mice following mechanical ventilation. Pearson’s r correlations between human soluble Aβ1–40 and Aβ1–42 levels and cerebral cytokine levels measured by the Meso Scale Discovery (MSD) multiplex inflammatory assay in age-matched ADtg mice (n = 8–9 mice/group). a–d Correlations between cerebral soluble Aβ1–40 levels in ADtg groups (MV and SB) and the following cerebral cytokines: a TNF-α, b IL-10, c IL-5, and d IL-1β. e, f Correlations between cerebral soluble Aβ1–42 and the following cerebral cytokines: e IL-10 and f IL-1β. Data from individual mice in MV (orange dots) and SB (yellow dots) groups are shown. Both r and p values, as well as 95% CI, dashed lines are shown as measured by Pearson’s r correlations