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. 2019 Feb 22;19:186. doi: 10.1186/s12879-019-3816-7

Table 1.

Vaccine effectiveness against RVGE hospitalization during the post-vaccine period by age group

Age Group Direct VE, % (95% CI) Indirect VE, %
(95% CI)
Overall VE, %
(95% CI)
Total VE, %
(95% CI)
< 1 80* (70, 87) 79* (66, 87) 88* (82, 92) 96* (93, 97)
1 92* (87, 95) 59* (33, 76) 79* (65, 88) 97* (95, 98)
2 87* (76, 93) 43* (4, 67) 68* (44, 83) 93* (86, 96)
3 96* (89, 99) 42 (− 2, 68) 71* (47, 84) 97* (93, 99)
4 81* (53, 93) 36 (− 25, 68) 59* (22, 79) 88* (70, 96)
0–4 87* (83, 90) 60* (48, 69) 78* (71, 83) 95* (93, 96)
5–9 47 (− 12, 79) 48* (30, 61) 50* (34, 63) 72* (42, 89)
10–14 46* (14, 67) Equivalent to indirect VEa
15–24 42* (10, 62)
25–44 56* (36, 70)
45–64 35* (9, 53)
All ages 69* (62, 76)

*Represents significance at the alpha = 0.05 level

aIndirect and overall VE are equivalent for children, adolescents, and adults over 9 years of age because there are no vaccinated individuals in these age groups